An independent Board of Directors governs MISO. The mission of the Board is to foster MISO's long-term success and corporate sustainability consistent with its responsibilities to Members, other stakeholders, governmental authorities and wholesale and end-use customers. Each member serves a three-year term and must meet specific qualifications designed to ensure an independent and qualified Board.

The Board performs a central role in achieving this goal by ensuring MISO management is capable of performing its duties and achieving its objectives consistent with MISO's strategic plan and core values. The Transmission Owners' Agreement requires that the Board meets at least quarterly.